Reactome | GRM3 [plasma membrane]

GRM3 [plasma membrane]

Stable Identifier

R-RNO-420509

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P31422

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM3 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM3 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
      - Metabotropic glutamate receptors bind glutamate (Rattus norvegicus)
        
        GRM1-8 [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM3 [plasma membrane] (Rattus norvegicus)
        
        GRM1-8:L-Glu [plasma membrane] (Rattus norvegicus)
        
        GRM1-8 [plasma membrane] (Rattus norvegicus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)
        
        GRM3 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P31422

Reference Genes

BioGPS Gene:24416

ENSEMBL:ENSRNOG00000005519

ENSEMBL:ENSRNOG00000005519.8

ENSEMBL:ENSRNOG00055018984

ENSEMBL:ENSRNOG00060012716

ENSEMBL:ENSRNOG00065018177

KEGG Gene (Rattus norvegicus):24416

Monarch:24416

NCBI Gene:24416

Reference Transcript

RefSeq:NM_001105712.1

Other Identifiers

10853267

1388189_at

17781053

24416

5618097

5704711

5848468

5995260

6003232

6149791

6352037

6439301

6519338

6584479

A_42_P514501

A_44_P146833

A_64_P014143

A_64_P129943

GE1256765

GE21867

GO:0004930

GO:0007186

GO:0016020

GO:0023052

GO:0060089

ILMN_1364857

M92076_at

PH_rn_0011479

PH_rn_0019693

Participates

as a member of

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Rattus norvegicus)

Inferred From

GRM3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001099182.1

ZINC - World Drugs

GRM3_RAT

ZINC - FDA approved

GRM3_RAT

ZINC - Substances

GRM3_RAT

ZINC - Biogenic

GRM3_RAT

ZINC target

P31422

PRO

P31422

RGD

2744

PDB

2E4X, 2E4U, 2E4V, 2E4Y, 2E4W

ZINC - Investigational

GRM3_RAT

ZINC - Metabolites

GRM3_RAT

Ensembl

ENSRNOP00000007572, ENSRNOG00000005519, ENSRNOT00000007572

ZINC - Predictions - Purchasable

GRM3_RAT

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