Reactome | AP2M1-2 [endocytic vesicle membrane]

AP2M1-2 [endocytic vesicle membrane]

Stable Identifier

R-RNO-416634

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

endocytic vesicle membrane

Synonyms

P84092

Locations in the PathwayBrowser

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Neuronal System (Rattus norvegicus)

- Transmission across Chemical Synapses (Rattus norvegicus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
    - Glutamate binding, activation of AMPA receptors and synaptic plasticity (Rattus norvegicus)
      - Trafficking of AMPA receptors (Rattus norvegicus)
        
        Trafficking of GluR2-containing AMPA receptors (Rattus norvegicus)
        
        Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Rattus norvegicus)
        
        AP2 complex [endocytic vesicle membrane] (Rattus norvegicus)
        
        AP2M1-2 [endocytic vesicle membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P84092 Ap2m1

Gene Names

Ap2m1

Chain

chain:1-435

Reference Genes

BioGPS Gene:116563 Ap2m1

KEGG:rno:116563 Ap2m1

Monarch:116563 Ap2m1

NCBI Gene:116563 Ap2m1

UCSC:P84092 Ap2m1

Reference Transcript

RefSeq:NM_053837.2 Ap2m1

Other Identifiers

10755448

116563

1398765_at

17670481

5650882

5666345

5827265

5850180

5862963

5974306

6138686

6270687

6313727

6313775

6354477

6373420

6439823

6470639

6494931

6535624

6541704

A_43_P14179

GE21776

GO:0005048

GO:0005886

GO:0005905

GO:0006886

GO:0006897

GO:0006900

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0030122

GO:0030131

GO:0031623

GO:0044325

GO:0045202

GO:0048488

GO:0061024

GO:0072583

GO:0097494

GO:0097718

GO:0098793

GO:0098794

GO:0098884

GO:0098978

GO:1903077

ILMN_1364100

PH_rn_0011578

rc_AI012807_at

Participates

as a component of

AP2 complex [endocytic vesicle membrane] (Rattus norvegicus)

Other forms of this molecule

AP2M1 [plasma membrane]

AP2M1 [lysosomal membrane]

AP2M1 [cytosol]

AP2M1 [clathrin-coated endocytic vesicle membrane]

Adaptor Protein 2 mu 1 subunit [plasma membrane]

AP2M1 [endolysosome membrane]

phospho-p-T156 AP2M1 [cytosol]

Inferred From

AP2M1-2 [endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_446289.1

ENSEMBL

ENSRNOP00000054900, ENSRNOG00000001709, ENSRNOT00000058092

PRO

P84092

RGD

620135

PDB

7OI5, 6YAH, 2PR9, 2BP5, 6YAE, 5WRL, 2VGL, 7OHZ, 7OFP, 2JKT, 6YAF, 7OG1, 6QH6, 6QH5, 1I31, 9FIW, 5FPI, 9FIX, 5C7Z, 9FIY, 7Z5C, 6RH6, 4UQI, 3ML6, 2XA7, 9UUK, 9UUJ, 9UUL, 7OIQ, 1HES, 2JKR, 1BW8, 1BXX, 3H85, 5WRM, 7OHO, 5WRK

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17301 ITGA2	1	ITGA2 [plasma membrane] (R-HSA-57562)	0.558	2
UniProt:Q60838	5	Dvl2 [cytosol] (R-MMU-4652689) phospho-Dvl2 [clathrin-coated endocytic vesicle] (R-MMU-5138444) Dvl2 [cytosol] (R-MMU-201694) phospho-Dvl2 [cytosol] (R-MMU-201706) phospho-Dvl2 [cytosol] (R-MMU-3772398)	0.558	4
UniProt:P19332	5	phospho-Mapt [cytosol] (R-RNO-9836400) Mapt [cytosol] (R-RNO-9619519) Mapt [cytosol] (R-RNO-350642) Mapt [cytosol] (R-RNO-350628) Mapt [cytosol] (R-RNO-201574)	0.462	2

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