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phospho-Icos [plasma membrane]
Stable Identifier
R-RNO-389927
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
p-Y180-ICOS, Q9R1T7
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Regulation of T cell activation by CD28 family (Rattus norvegicus)
Co-stimulation by ICOS (Rattus norvegicus)
PI3K binds ICOS (Rattus norvegicus)
ICOS:PI3K [plasma membrane] (Rattus norvegicus)
phospho-Icos [plasma membrane] (Rattus norvegicus)
phospho-Icos [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
ICOS:PI3K [plasma membrane] (Rattus norvegicus)
phospho-Icos [plasma membrane] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
ICOS:PI3K [plasma membrane] (Rattus norvegicus)
phospho-Icos [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9R1T7
Gene Names
Icos
Reference Genes
BioGPS Gene:64545 Icos
ENSEMBL:ENSRNOG00000046196
ENSEMBL:ENSRNOG00055021865
ENSEMBL:ENSRNOG00060023212
ENSEMBL:ENSRNOG00065026477
KEGG:rno:64545 Icos
Monarch:64545 Icos
NCBI Gene:64545 Icos
UCSC:Q9R1T7 Icos
Reference Transcript
RefSeq:XM_008767136.4 Icos
RefSeq:NM_022610.3 Icos
RefSeq:NM_001431818.1 Icos
RefSeq:XM_006245037.5 Icos
Other Identifiers
10940522
1368783_at
1370769_a_at
1393329_at
17881979
17881980
5995493
64545
6710680
6739365
A_44_P172601
A_44_P325766
GE1262375
GO:0002376
GO:0005886
GO:0030154
GO:0031295
GO:0038023
GO:0061470
rc_AA996552_at
Participates
as an input of
PI3K binds ICOS (Rattus norvegicus)
as a component of
ICOS:PI3K [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Icos [plasma membrane]
Inferred From
p-Y180-ICOS [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 180 (in Homo sapiens)
Coordinate
180
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_008765358.1
,
XP_006245099.1
,
NP_072132.1
,
NP_001418747.1
ENSEMBL
ENSRNOT00000071226
,
ENSRNOG00000046196
,
ENSRNOP00000064455
PRO
Q9R1T7
GlyGen
Q9R1T7
RGD
620123
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