Reactome | Cep41 [cytosol]

Cep41 [cytosol]

Stable Identifier

R-RNO-380269

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

CEP41, Q4KM37

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Rattus norvegicus)

- Cilium Assembly (Rattus norvegicus)
  - Assembly of the 9+0 primary cilium (Rattus norvegicus)
    - Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
      - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - C2CD3 binds the mother centriole (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - MARK4 binds ODF2 in the centriole (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - Recruitment of transition zone proteins (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
      - The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Cep41 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q4KM37

Gene Names

Cep41

Reference Genes

BioGPS Gene:500069 Cep41

ENSEMBL:ENSRNOG00000010950

KEGG:rno:500069 Cep41

Monarch:500069 Cep41

NCBI Gene:500069 Cep41

UCSC:Q4KM37 Cep41

Reference Transcript

RefSeq:NM_001025770.2 Cep41

Other Identifiers

10861591

1374270_at

1382409_at

1382865_at

17790319

500069

5620727

5769181

5840520

5865115

5927903

6002160

6021216

6048657

6237384

6241054

6271522

6365683

6481515

6547164

6556704

6594612

6595078

6743439

A_44_P576579

A_44_P945759

GE1260336

GE1267084

GE12962

GO:0005813

GO:0005814

GO:0005815

GO:0005929

GO:0036064

GO:0043226

GO:0044782

GO:0060271

ILMN_1372140

PH_rn_0006990

rc_AA964789_at

rc_AI072515_at

Participates

as a component of

Inferred From

CEP41 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001020941.1

ENSEMBL

ENSRNOT00000014621, ENSRNOP00000014621, ENSRNOG00000010950

PRO

Q4KM37

RGD

1562034

Cite Us!