Reactome | Dimerization of p-S133-Creb1

Dimerization of p-S133-Creb1

Stable Identifier

R-RNO-379842

Type

Reaction [binding]

Species

Rattus norvegicus

Compartment

nucleoplasm

ReviewStatus

5/5

General

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SVG | | PPTX | SBGN

Homodimerization of rat Creb1 is induced by activating phosphorylation of Creb1 on serine residue S133 (Yamamoto et al. 1988) and involves the C-terminal DNA binding and dimerization domain (Yun et al. 1990).

Literature References

PubMed ID	Title	Journal	Year
2900470	Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB Biggs, WH, Yamamoto, KK, Gonzalez, GA, Montminy, MR	Nature	1988
2146495	DNA-binding and dimerization domains of adenosine 3',5'- cyclic monophosphate-responsive protein CREB reside in the carboxyl-terminal 66 amino acids Dumoulin, M, Yun, YD, Habener, JF	Mol Endocrinol	1990