Reactome | Ccr8 [plasma membrane]

Ccr8 [plasma membrane]

Stable Identifier

R-RNO-373237

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

CCR8, D4ADE0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CCR8:CCL1 [plasma membrane] (Rattus norvegicus)
        
        Ccr8 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CCR8:CCL1 [plasma membrane] (Rattus norvegicus)
        
        Ccr8 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Chemokine receptors bind chemokines (Rattus norvegicus)
        
        CCR8 binds CCL1 (Rattus norvegicus)
        
        CCR8:CCL1 [plasma membrane] (Rattus norvegicus)
        
        Ccr8 [plasma membrane] (Rattus norvegicus)
        
        Ccr8 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4ADE0

Gene Names

Ccr8

Reference Genes

BioGPS Gene:301066 Ccr8

ENSEMBL:ENSRNOG00000026759

KEGG:rno:301066 Ccr8

Monarch:301066 Ccr8

NCBI Gene:301066 Ccr8

UCSC:D4ADE0 Ccr8

Reference Transcript

RefSeq:NM_001427325.1 Ccr8

Other Identifiers

10914301

17848872

301066

5650982

6378616

6402825

A_44_P309666

GO:0002376

GO:0004930

GO:0004950

GO:0006935

GO:0006955

GO:0007186

GO:0007204

GO:0016020

GO:0016493

ILMN_1363495

PH_rn_0002511

Participates

as an input of

CCR8 binds CCL1 (Rattus norvegicus)

as a member of

CCR1,2,8 [plasma membrane] (Rattus norvegicus)

as a component of

CCR8:CCL1 [plasma membrane] (Rattus norvegicus)

Inferred From

CCR8 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001414254.1

ENSEMBL

ENSRNOP00000029724, ENSRNOG00000026759, ENSRNOT00000029766

RGD

1304893

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