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DISC:procaspase-8 [plasma membrane]
Stable Identifier
R-RNO-3465443
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Caspase activation via extrinsic apoptotic signalling pathway (Rattus norvegicus)
Caspase activation via Death Receptors in the presence of ligand (Rattus norvegicus)
Regulation by c-FLIP (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at DISC (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
Regulation of necroptotic cell death (Rattus norvegicus)
CASP8 activity is inhibited (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
FLIP(S) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Casp8 [cytosol]
(Rattus norvegicus)
DISC [plasma membrane]
(Rattus norvegicus)
Participates
as an input of
FLIP(L) and procaspase-8 form heterodimer (Rattus norvegicus)
FLIP(S) and procaspase-8 form heterodimer (Rattus norvegicus)
as a component of
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Rattus norvegicus)
Inferred From
DISC:procaspase-8 [plasma membrane]
(Homo sapiens)
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