Reactome | Cbx6 [nucleoplasm]

Cbx6 [nucleoplasm]

Stable Identifier

R-RNO-3229071

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

CBX6, E9PT11

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by RUNX1 (Rattus norvegicus)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Rattus norvegicus)
        
        RUNX1 binds PRC1 complexes (Rattus norvegicus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4 [nucleoplasm] (Rattus norvegicus)
        
        CBX2,CBX4,CBX6,CBX8 [nucleoplasm] (Rattus norvegicus)
        
        Cbx6 [nucleoplasm] (Rattus norvegicus)
        
        RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Rattus norvegicus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4 [nucleoplasm] (Rattus norvegicus)
        
        CBX2,CBX4,CBX6,CBX8 [nucleoplasm] (Rattus norvegicus)
        
        Cbx6 [nucleoplasm] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Intracellular signaling by second messengers (Rattus norvegicus)
  - PIP3 activates AKT signaling (Rattus norvegicus)
    - PTEN Regulation (Rattus norvegicus)
      - Regulation of PTEN gene transcription (Rattus norvegicus)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Rattus norvegicus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Rattus norvegicus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4 [nucleoplasm] (Rattus norvegicus)
        
        CBX2,CBX4,CBX6,CBX8 [nucleoplasm] (Rattus norvegicus)
        
        Cbx6 [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Rattus norvegicus)
        
        PRC1.4 [nucleoplasm] (Rattus norvegicus)
        
        CBX2,CBX4,CBX6,CBX8 [nucleoplasm] (Rattus norvegicus)
        
        Cbx6 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:E9PT11

Gene Names

Cbx6

Reference Genes

BioGPS Gene:315136 Cbx6

ENSEMBL:ENSRNOG00000046955

Monarch:315136 Cbx6

NCBI Gene:315136 Cbx6

UCSC:E9PT11 Cbx6

Reference Transcript

RefSeq:NM_001401046.1 Cbx6

Other Identifiers

10905500

1374703_at

1375307_at

17839230

315136

5757791

5802626

5851845

5862935

5905100

5963850

5996757

6007535

6076001

6079967

6089245

6205152

6275469

6404196

6438744

6532171

6627243

6735910

A_44_P541615

A_64_P139048

A_64_P139054

GE1251356

GE1298708

GE18184

GO:0000122

GO:0000785

GO:0000792

GO:0003682

GO:0003723

GO:0003727

GO:0005634

GO:0005654

GO:0006325

GO:0006355

GO:0016604

GO:0031519

GO:0035102

ILMN_1375506

ILMN_1376701

PH_rn_0006125

rc_AI072945_at

rc_AI137423_at

Participates

as a member of

CBX2,CBX4,CBX6,CBX8 [nucleoplasm] (Rattus norvegicus)

Inferred From

CBX6 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSRNOG00000046955, ENSRNOP00000061325, ENSRNOT00000068033

RGD

1307314