Reactome | Dnajc6 [cytosol]

Dnajc6 [cytosol]

Stable Identifier

R-RNO-264472

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

DNAJC6, A0A8I5ZWX0

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - Clathrin-mediated endocytosis (Rattus norvegicus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Rattus norvegicus)
      - GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        GAK,DNAJC6 [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
  - trans-Golgi Network Vesicle Budding (Rattus norvegicus)
    - Golgi Associated Vesicle Biogenesis (Rattus norvegicus)
      - trans-Golgi Network Derived Vesicle Uncoating (Rattus norvegicus)
        
        HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)
    - Lysosome Vesicle Biogenesis (Rattus norvegicus)
      - trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Rattus norvegicus)
        
        HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)
        
        Dnajc6 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZWX0

Gene Names

Dnajc6

Reference Genes

BioGPS Gene:313409 Dnajc6

ENSEMBL:ENSRNOG00000052887

Monarch:313409 Dnajc6

NCBI Gene:313409 Dnajc6

UCSC:A0A8I5ZWX0 Dnajc6

Reference Transcript

Other Identifiers

10870269

1377125_at

1386648_at

17800183

313409

5642443

5785319

5875029

5884171

5949373

6022939

6027539

6067712

6117124

6133949

6234461

6277659

6332505

6392430

6435290

6440052

6444754

6471347

6478272

6488301

6506048

6531369

6536459

6581975

6596070

6608023

6620059

6631979

6698860

6719443

A_42_P536403

A_44_P520725

A_44_P905187

GE1131831

GO:0003824

GO:0004721

GO:0005737

GO:0008150

GO:0014069

GO:0016191

GO:0016192

GO:0016311

GO:0016787

GO:0017124

GO:0030136

GO:0030276

GO:0031410

GO:0031982

GO:0036465

GO:0043226

GO:0045202

GO:0072318

GO:0072583

GO:0098894

GO:0140096

GO:1905443

GO:2000369

ILMN_1369280

PH_rn_0012664

PH_rn_0020298

rc_AI228654_at

Participates

as a component of

HSC70:Auxillin Complex [cytosol] (Rattus norvegicus)

as a member of

GAK,DNAJC6 [cytosol] (Rattus norvegicus)

Inferred From

DNAJC6 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006238511.1, XP_038965846.1

ENSEMBL

ENSRNOT00000116178, ENSRNOG00000052887, ENSRNOP00000084012

RGD

1309900

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