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CD19 Signalosome [plasma membrane]
Stable Identifier
R-RNO-2076233
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Rattus norvegicus)
CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Rattus norvegicus)
CD19 Signalosome [plasma membrane] (Rattus norvegicus)
p-CD19:VAV binds PI3K and GRB2 (Rattus norvegicus)
CD19 Signalosome [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
CD19 Signalosome [plasma membrane] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
CD19 Signalosome [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Grb2 [plasma membrane]
(Rattus norvegicus)
phospho-Cd19 [plasma membrane]
(Rattus norvegicus)
PIK3CD:PIK3R1 [plasma membrane]
(Rattus norvegicus)
Vav1 [plasma membrane]
(Rattus norvegicus)
Participates
as an output of
p-CD19:VAV binds PI3K and GRB2 (Rattus norvegicus)
as a member of
Activator:PI3K [plasma membrane] (Rattus norvegicus)
Inferred From
CD19 Signalosome [plasma membrane]
(Homo sapiens)
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