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phospho-Mdm2 [cytosol]
Stable Identifier
R-RNO-198638
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
p-S166,S188-MDM2, A0A8I6G5V3
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
Regulation of TP53 Activity (Rattus norvegicus)
Regulation of TP53 Expression and Degradation (Rattus norvegicus)
Regulation of TP53 Degradation (Rattus norvegicus)
AKT phosphorylates MDM2 (Rattus norvegicus)
phospho-Mdm2 [cytosol] (Rattus norvegicus)
MDM2 translocates to the nucleus (Rattus norvegicus)
phospho-Mdm2 [cytosol] (Rattus norvegicus)
SGK1 phosphorylates MDM2 (Rattus norvegicus)
phospho-Mdm2 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
AKT phosphorylates targets in the cytosol (Rattus norvegicus)
AKT phosphorylates MDM2 (Rattus norvegicus)
phospho-Mdm2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I6G5V3
Gene Names
Mdm2
Reference Genes
ENSEMBL:ENSRNOG00000006304
ENSEMBL:ENSRNOG00000006304.8 Mdm2
Other Identifiers
10902564
1383288_at
1383485_at
1384427_at
17836020
314856
5692726
5791899
5915045
6108596
6150437
6178586
6242309
6330283
6358230
6527698
6589842
A_44_P634946
GE1249606
GE1265548
GO:0000122
GO:0000278
GO:0001568
GO:0001974
GO:0002027
GO:0002039
GO:0003013
GO:0003170
GO:0003181
GO:0003203
GO:0003281
GO:0003283
GO:0003723
GO:0003824
GO:0004842
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0006351
GO:0006355
GO:0006511
GO:0006915
GO:0006977
GO:0007089
GO:0007507
GO:0008097
GO:0008270
GO:0010468
GO:0012501
GO:0016567
GO:0016604
GO:0016740
GO:0016874
GO:0017053
GO:0019899
GO:0019904
GO:0023052
GO:0030154
GO:0030163
GO:0031625
GO:0031648
GO:0032436
GO:0032991
GO:0034504
GO:0036211
GO:0042176
GO:0042802
GO:0043021
GO:0043066
GO:0043130
GO:0043226
GO:0043518
GO:0045184
GO:0045787
GO:0045892
GO:0045931
GO:0046677
GO:0048856
GO:0051149
GO:0051603
GO:0051726
GO:0051865
GO:0060411
GO:0061630
GO:0061663
GO:0065003
GO:0071456
GO:0071480
GO:0072717
GO:0097718
GO:0140096
GO:1901797
GO:1902254
GO:1990000
ILMN_1364670
PH_rn_0007193
rc_AA849796_at
rc_AI639488_at
Participates
as an input of
MDM2 translocates to the nucleus (Rattus norvegicus)
as an output of
AKT phosphorylates MDM2 (Rattus norvegicus)
SGK1 phosphorylates MDM2 (Rattus norvegicus)
Other forms of this molecule
Mdm2 [nucleoplasm]
Mdm2 [nucleoplasm]
Mdm2 [plasma membrane]
Mdm2 [endocytic vesicle membrane]
phospho-Mdm2 [nucleoplasm]
phospho-Mdm2 [nucleoplasm]
phospho-Mdm2 [nucleoplasm]
Mdm2 [nucleoplasm]
Mdm2 [cytosol]
phospho-Mdm2 [nucleoplasm]
Inferred From
p-S166,S188-MDM2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 166 (in Homo sapiens)
Coordinate
166
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 188 (in Homo sapiens)
Coordinate
188
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
Ensembl
ENSRNOT00000096862
,
ENSRNOP00000079885
,
ENSRNOG00000006304
RGD
1305332
PDB
8HSV
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