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What is Reactome ?
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Ripk1 [cytosol]
Stable Identifier
R-RNO-168651
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
RIPK1, D3ZYL0
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
IKK complex recruitment mediated by RIP1 (Rattus norvegicus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRIF-mediated programmed cell death (Rattus norvegicus)
Caspase-8 processing within TLR4 complex (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIP3 binds TRIF to mediate necroptosis (Rattus norvegicus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Rattus norvegicus)
RIP3:RIP1:TICAM1:activated TLR4 [endosome membrane] (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRIF:activated TLR4 [endosome membrane] (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TLR4-induced ripoptosome assembly (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Deubiquitination (Rattus norvegicus)
Ovarian tumor domain proteases (Rattus norvegicus)
TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Rattus norvegicus)
TNFAIP3:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFAIP3 (A20) ubiquitinates RIPK1 (Rattus norvegicus)
TNFAIP3:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Ub-specific processing proteases (Rattus norvegicus)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Rattus norvegicus)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
USP21 deubiquitinates RIPK1,DDX58 (Rattus norvegicus)
USP21:RIPK1,DDX58 [cytosol] (Rattus norvegicus)
RIPK1, DDX58 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Caspase activation via extrinsic apoptotic signalling pathway (Rattus norvegicus)
Caspase activation via Death Receptors in the presence of ligand (Rattus norvegicus)
Caspase-8 processing within TLR4 complex (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Dimerization of procaspase-8 (Rattus norvegicus)
TNF-mediated dimerization of procaspase-8 (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Regulation by c-FLIP (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at DISC (Rattus norvegicus)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
RIPK1 is phosphorylated (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK3 is phosphorylated (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Regulation of necroptotic cell death (Rattus norvegicus)
CASP8 activity is inhibited (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(L) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
FLIP(S) and procaspase-8 form heterodimer (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
DISC:procaspase-8:FLIP(S) [plasma membrane] (Rattus norvegicus)
DISC:procaspase-8 [plasma membrane] (Rattus norvegicus)
DISC [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8 (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Small molecule inhibitor binds RIPK1, RIPK3 (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
K63polyUb-RIPK1 is deubiquitinated (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1 binds STUB1 (Rattus norvegicus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8 (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1 is cleaved by CASP8:FLIP(L) (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Rattus norvegicus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Rattus norvegicus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
ULK1 phosphorylates RIPK1 at S357 (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFR1-induced NF-kappa-B signaling pathway (Rattus norvegicus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TNFR1-induced proapoptotic signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1 complex binds FADD (Rattus norvegicus)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
Ripk1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZYL0
Gene Names
Ripk1
Reference Genes
BioGPS Gene:306886 Ripk1
ENSEMBL:ENSRNOG00000017787
ENSEMBL:ENSRNOG00000017787.6 Ripk1
KEGG Gene (Rattus norvegicus):306886 Ripk1
Monarch:306886 Ripk1
NCBI Gene:306886 Ripk1
UCSC:D3ZYL0 Ripk1
Reference Transcript
RefSeq:XM_017600527.1 Ripk1
RefSeq:XM_017600523.1 Ripk1
RefSeq:XM_017600526.1 Ripk1
RefSeq:XM_017600529.1 Ripk1
RefSeq:NM_001107350.1 Ripk1
RefSeq:XM_017600525.1 Ripk1
RefSeq:XM_017600524.1 Ripk1
RefSeq:XM_017600528.1 Ripk1
Other Identifiers
10798108
1371529_at
1391543_at
17719090
306886
5784930
5816297
5927050
5990737
6028181
6035532
6091428
6102779
6107295
6213775
6266550
6267050
6289009
6313681
6345582
6404740
6407078
6498751
6557313
6581673
6584181
A_42_P722994
A_44_P156830
GE1183111
GE18375
GO:0001934
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005123
GO:0005515
GO:0005524
GO:0005739
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006915
GO:0006954
GO:0006979
GO:0007165
GO:0010628
GO:0012501
GO:0016740
GO:0023052
GO:0030154
GO:0030163
GO:0031047
GO:0031264
GO:0031625
GO:0032757
GO:0032760
GO:0032991
GO:0034612
GO:0035556
GO:0035591
GO:0036211
GO:0042327
GO:0042802
GO:0042803
GO:0043065
GO:0043066
GO:0043068
GO:0043123
GO:0043124
GO:0043226
GO:0043235
GO:0043410
GO:0044877
GO:0045651
GO:0045944
GO:0046330
GO:0048856
GO:0050729
GO:0060090
GO:0060545
GO:0060546
GO:0062100
GO:0065003
GO:0070105
GO:0070231
GO:0070266
GO:0070301
GO:0070513
GO:0071356
GO:0071363
GO:0097191
GO:0097300
GO:0097342
GO:0097343
GO:0097527
GO:0140096
GO:1900119
GO:1901026
GO:1903265
GO:1903800
GO:1990000
GO:2000377
GO:2001237
GO:2001238
GO:2001240
ILMN_1350981
PH_rn_0008124
rc_AI007920_at
Participates
as a component of
TNFAIP3:RIPK1 [cytosol] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TRAF2:TRADD:RIPK1 [cytosol] (Rattus norvegicus)
RIPK1:RIPK3 [cytosol] (Rattus norvegicus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Rattus norvegicus)
as a member of
RIPK1, DDX58 [cytosol] (Rattus norvegicus)
TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] (Rattus norvegicus)
as an input of
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
RIPK1 binds STUB1 (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Rattus norvegicus)
Other forms of this molecule
Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
phospho-Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
Ripk1 [cytosol]
Inferred From
RIPK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001100820.1
,
XP_017456017.1
,
XP_017456016.1
,
XP_017456015.1
,
XP_017456014.1
,
XP_017456013.1
,
XP_017456012.1
,
XP_017456018.1
Ensembl
ENSRNOG00000017787
,
ENSRNOT00000023962
,
ENSRNOP00000023962
RGD
1310158
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