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C3 [extracellular region]
Stable Identifier
R-RNO-166821
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
extracellular region
Synonyms
C3 beta chain, P01026
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Complement cascade (Rattus norvegicus)
Activation of C3 and C5 (Rattus norvegicus)
Activation of C5 (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
C3 binds C3 inhibitors (Rattus norvegicus)
C3:C3 inhibitors [extracellular region] (Rattus norvegicus)
Complement factor 3 [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor 3 [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cleavage of C3 by C3 convertases (Rattus norvegicus)
C3 convertases [plasma membrane] (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor 3 [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Formation of classic pathway C5 convertase (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Initial triggering of complement (Rattus norvegicus)
Alternative complement activation (Rattus norvegicus)
C3b binds to cell surface (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Spontaneous hydrolysis of C3 thioester (Rattus norvegicus)
C3(H2O) [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor 3 [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Regulation of Complement cascade (Rattus norvegicus)
CD46 binds C3b (Rattus norvegicus)
CD46:Cell surface:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CFHR dimers bind C3b (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:C3b:CFHR dimers [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor I binds to MCP, CR1:C4b, C3b (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CR1:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CR1:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor I binds to extracellular Factor H:C3b (Rattus norvegicus)
CFH:C3b [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CFI:CFH:C3b [extracellular region] (Rattus norvegicus)
CFH:C3b [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Complement factor I binds to membrane-associated Factor H:C3b (Rattus norvegicus)
CFI:CFH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor H binds to C3b (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CFH:C3b [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor H binds to membrane-associated C3b (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor I cleaves iC3b (Rattus norvegicus)
C3c [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor I inactivates Factor H-boundC3b (Rattus norvegicus)
CFI:CFH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:FH,FHR3:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor I inactivates MCP/CR1-bound C4b/C3b (Rattus norvegicus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
CR1:C3b [plasma membrane] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
Factor I inactivates plasma Factor H-bound C3b (Rattus norvegicus)
CFI:CFH:C3b [extracellular region] (Rattus norvegicus)
CFH:C3b [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
iC3b [extracellular region] (Rattus norvegicus)
C3 [extracellular region] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P01026
Gene Names
C3
Reference Genes
BioGPS Gene:24232 C3
ENSEMBL:ENSRNOG00000046834
KEGG:rno:24232 C3
Monarch:24232 C3
NCBI Gene:24232 C3
UCSC:P01026 C3
Reference Transcript
RefSeq:NM_016994.2 C3
Participates
as a component of
iC3b [extracellular region] (Rattus norvegicus)
C3c [extracellular region] (Rattus norvegicus)
Complement factor 3 [extracellular region] (Rattus norvegicus)
C3b [extracellular region] (Rattus norvegicus)
C3(H2O) [extracellular region] (Rattus norvegicus)
Other forms of this molecule
C3 [extracellular region]
C3 [secretory granule lumen]
C3 [secretory granule lumen]
C3 [azurophil granule lumen]
C3 [azurophil granule lumen]
phospho-C3 [endoplasmic reticulum lumen]
C3 [endoplasmic reticulum lumen]
C3 [extracellular region]
C3 [extracellular region]
C3 [extracellular region]
C3 [extracellular region]
C3 [plasma membrane]
C3 [plasma membrane]
C3 [extracellular region]
C3 [plasma membrane]
C3 [plasma membrane]
C3 [plasma membrane]
C3 [extracellular region]
C3 [extracellular region]
C3 [extracellular region]
C3 [extracellular region]
Inferred From
C3 beta chain [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_058690.2
PRO
P01026
GlyGen
P01026
RGD
2232
PDB
1QSJ
,
1QQF
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