phosphorylated perilipin + H2O -> perilipin + orthophosphate

Stable Identifier
R-RNO-163609
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
cytosol, lipid droplet
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
phosphorylated perilipin + H2O -> perilipin + orthophosphate
Rat perilipin is dephosphorylated by protein phosphatase 1 (Clifford et al. 1998). All three protein phosphatase 1 isoforms appear competent to carry out this reaction and there are no data to indicate which one preferentially acts on perilipin in vivo. Dephosphorylation of human perilipin has not been studied in detail, so the human reaction is inferred from the well-studied rat one.
Literature References
PubMed ID Title Journal Year
9755872 Dephosphorylation of perilipin by protein phosphatases present in rat adipocytes

Clifford, GM, McCormick, DK, Londos, C, Vernon, RG, Yeaman, SJ

FEBS Lett 1998
Participants
Input
Output
Catalyst Activity

protein serine/threonine phosphatase activity of PP1 catalytic subunit [cytosol]

Physical Entity
PP1 catalytic subunit [cytosol] (Rattus norvegicus)
Activity
protein serine/threonine phosphatase activity (GO:0004722)
Orthologous Events
phosphorylated perilipin + H2O -> perilipin + orthophosphate (Homo sapiens)
Authored
D'Eustachio, P  (2005-05-02)
Created
D'Eustachio, P  (2005-05-02)
Cite Us!