Reactome | Ash2l [nucleoplasm]

Ash2l [nucleoplasm]

Stable Identifier

R-RNO-1629834

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

ASH2L, D3ZTV7

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Regulation of T cell activation by CD28 family (Rattus norvegicus)
    - Co-inhibition by PD-1 (Rattus norvegicus)
      - Regulation of PD-L1(CD274) expression (Rattus norvegicus)
        
        Regulation of PD-L1(CD274) transcription (Rattus norvegicus)
        
        MLL1,MLL3 complex binding to CD274 gene chromatin (Rattus norvegicus)
        
        CD274 gene chromatin:MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        Trimethylation of CD274 gene chromatin by MLL1/3 complex (Rattus norvegicus)
        
        CD274 gene chromatin:MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3_complex:CD274 gene H3K4me3 chromatin [nucleoplasm] (Rattus norvegicus)
        
        MLL1,MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL1 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        MLL3 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by WNT (Rattus norvegicus)
  - TCF dependent signaling in response to WNT (Rattus norvegicus)
    - Deactivation of the beta-catenin transactivating complex (Rattus norvegicus)
      - APC promotes disassembly of beta-catenin transactivation complex (Rattus norvegicus)
        
        MLL2 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
    - Formation of the beta-catenin:TCF transactivating complex (Rattus norvegicus)
      - Recruitment of MLL2 methyltransferase complex (Rattus norvegicus)
        
        MLL2 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
        
        MLL2 complex [nucleoplasm] (Rattus norvegicus)
        
        WRAD complex [nucleoplasm] (Rattus norvegicus)
        
        Ash2l [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZTV7

Gene Names

Ash2l

Reference Genes

BioGPS Gene:290829 Ash2l

ENSEMBL:ENSRNOG00000014875

Monarch:290829 Ash2l

NCBI Gene:290829 Ash2l

UCSC:D3ZTV7 Ash2l

Reference Transcript

RefSeq:NM_001106089.1 Ash2l

Other Identifiers

10788803

1388871_at

1389719_at

17708572

290829

5622739

5656461

5675844

5735678

5919632

5963914

6014335

6077502

6179237

6230500

6300524

6310688

6367505

6401931

6434040

6532781

6615671

6684079

6685792

6723620

A_44_P210791

GE17181

GE19148

GO:0000791

GO:0000976

GO:0003677

GO:0005515

GO:0005634

GO:0006325

GO:0006355

GO:0006974

GO:0008013

GO:0008270

GO:0008284

GO:0010468

GO:0010557

GO:0035097

GO:0043627

GO:0044665

GO:0044666

GO:0045815

GO:0045944

GO:0046872

GO:0048188

GO:0071339

ILMN_1361125

PH_rn_0006974

rc_AI013540_at

Participates

as an input of

Formation of the RBBP5:ASH2L heterodimer (Rattus norvegicus)

as a component of

Inferred From

ASH2L [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001099559.1

ENSEMBL

ENSRNOT00000020181, ENSRNOG00000014875, ENSRNOP00000020181

RGD

1305632

Cite Us!