Persulfide sulfur is transferred onto sulfite

Stable Identifier
R-RNO-1614611
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
mitochondrial inner membrane, mitochondrial matrix
ReviewStatus
5/5
General
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Persulfide sulfur is transferred onto sulfite
The main reaction catalyzed by rhodanase is not the name-giving detoxification of cyanide to thiocyanate, but the transfer of a sulfur atom from Sqr-S-SH onto sulfite yielding thiosulfate during sulfide oxidation (Hildebrandt & Grieshaber, 2008).
Literature References
PubMed ID Title Journal Year
18494801 Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

Hildebrandt, TM, Grieshaber, MK

FEBS J 2008
Participants
Input
Output
Catalyst Activity

sulfurtransferase activity of rhodanase [mitochondrial matrix]

Physical Entity
rhodanase [mitochondrial matrix] (Rattus norvegicus)
Activity
sulfurtransferase activity (GO:0016783)
Orthologous Events
Persulfide sulfur is transferred onto sulfite (Homo sapiens)
Authored
Stephan, R  (2010-10-24)
Created
Jassal, B  (2011-09-29)
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