Persulfide sulfur is transferred onto sulfite

Stable Identifier
R-HSA-1614618
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane, mitochondrial matrix
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Persulfide sulfur is transferred onto sulfite
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The main reaction catalyzed by rhodanase is not the name-giving detoxification of cyanide to thiocyanate, but the transfer of a sulfur atom from SQR-S-SH onto sulfite yielding thiosulfate during sulfide oxidation. The activity of human rhodanase was inferred from the rat orthologue by Hildebrandt & Grieshaber, 2008.

Literature References
PubMed ID Title Journal Year
18494801 Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

Hildebrandt, TM, Grieshaber, MK

FEBS J 2008
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
sulfurtransferase activity of TST [mitochondrial matrix]
Physical Entity
TST [mitochondrial matrix]
Activity
sulfurtransferase activity (0016783)
Inferred From
Persulfide sulfur is transferred onto sulfite (Rattus norvegicus)
Authored
Stephan, R  (2010-10-24)
Reviewed
D'Eustachio, P  (2011-10-13)
Created
Jassal, B  (2011-09-29)