p-S173 MITF-M binds YWHA dimers

Stable Identifier
R-NUL-9926485
Type
Reaction [binding]
Species
Chlorocebus sabaeus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p-S173 MITF-M binds YWHA dimers
Based on co-IP and GST pulldown studies in COS-7 cells, MITF-M binds to dimers of 14-3-3 proteins YWHAZ, E, B, H and G. Binding is enhanced by MARK3/CTAK1-dependent phosphorylation of S173, and disrupted by treatment of cells with CSF or TNFSF11 (also known as RANKL) (Bronisz et al, 2006).
Literature References
PubMed ID Title Journal Year
16822840 Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors

Bronisz, A, Sharma, SM, Hu, R, Godlewski, J, Tzivion, G, Mansky, KC, Ostrowski, MC

Mol Biol Cell 2006
Participants
Input
Output
Orthologous Events
p-S173 MITF-M binds YWHA dimers (Homo sapiens)
Authored
Steingrímsson, E  (2024-11-05)
Vu, HN  (2024-11-05)
Reviewed
Vu, HN  (2024-11-05)
Steingrímsson, E  (2024-11-05)
Created
Rothfels, K  (2024-11-01)
Cite Us!