Ntrk2 phosohorylates CDK5

Stable Identifier
R-NUL-9032945
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ntrk2 phosohorylates CDK5
In an in vitro kinase assays, purified recombinant rat Ntrk2 (TrkB) phosphorylated purified recombinant human CDK5 on tyrosine residue Y15 (Cheung et al. 2007).
Literature References
PubMed ID Title Journal Year
17341134 Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons

Cheung, ZH, Chin, WH, Chen, Y, Ng, YP, Ip, NY

PLoS Biol. 2007
Participants
Input
Output
Catalyst Activity

protein tyrosine kinase activity of Ntrk2 [plasma membrane]

Physical Entity
Ntrk2 [plasma membrane] (Rattus norvegicus)
Activity
protein tyrosine kinase activity (GO:0004713)
Orthologous Events
NTRK2 phosphorylates CDK5 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-01-05)
Reviewed
Antila, H  (2018-02-13)
Castrén, E  (2018-02-13)
Created
Orlic-Milacic, M  (2017-12-20)
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