NTRK2 phosphorylates CDK5

Stable Identifier
R-HSA-9032854
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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NTRK2 phosphorylates CDK5
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BDNF-activated NTRK2 (TRKB) phosphorylates CDK5 on tyrosine residue Y15, thus increasing CDK5 catalytic activity (Cheung et al. 2007).

Participants
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Output
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as an event of
Catalyst Activity

protein tyrosine kinase activity of BDNF:p-5Y-NTRK2 homodimer:CDK5:p35 [plasma membrane]

Physical Entity
BDNF:p-5Y-NTRK2 homodimer:CDK5:p35 [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Inferred From
Ntrk2 phosohorylates CDK5 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-01-05)
Reviewed
Castrén, E  (2018-02-13)
Antila, H  (2018-02-13)
Created
Orlic-Milacic, M  (2017-12-18)
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