Pig Syk binds human Vav1

Stable Identifier
R-NUL-437945
Type
Reaction [binding]
Species
Sus scrofa
Compartment
General
SVG |   | PPTX  | SBGN
Pig Syk binds human Vav1

The SH2 region of Vav1 binds to Syk at a site including phosphorylated tyrosine Y348. Mutation of this residue to F abolishes binding and subsequent Vav1 phosphorylation. Vav2 has also been shown to bind Syk.

Literature References
PubMed ID Title Journal Year
8986718 Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

Deckert, M, Tartare-Deckert, S, Couture, C, Mustelin, T, Altman, A

Immunity 1996
Participants
Orthologous Events
Authored
Reviewed
Created
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