Mouse emilin-1 binds human elastin and mouse fibulin-5

Stable Identifier
R-NUL-2426460
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Mouse emilin-1 binds human elastin and mouse fibulin-5

Elastin microfibril interface located protein (EMILIN)-1 is localized to the microfibril-elastin interface (Bressan et al. 1993). It can bind elastin and fibulin-5 (Zanetti et al. 2004). Emilin1 knockout mice have ultrastructural alterations of the elastic fibers in aorta and skin, abnormal cell morphology and anchorage of endothelial and smooth muscle cells to elastic lamellae, and abnormal elastic fibers in cultured embryonic fibroblasts.

Literature References
PubMed ID Title Journal Year
14701737 EMILIN-1 deficiency induces elastogenesis and vascular cell defects

Colombatti, A, Braghetta, P, Bressan, GM, Bonaldo, P, Doliana, R, Mura, I, Sabatelli, P, Zanetti, M, Volpin, D

Mol. Cell. Biol. 2004
Participants
Orthologous Events
Authored
Reviewed
Created
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