Shikimate results from hydration of DHS

Stable Identifier
R-MTU-964842
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
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The dimeric form of AroE catalyzes the hydration of dehydroshikimate. The reaction is reversible with high efficiency (Magalhaes et al, 2002; Fonseca et al, 2006).

Literature References
PubMed ID Title Journal Year
12356471 Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv

Magalhães, ML, Pereira, CP, Basso, LA, Santos, DS

Protein Expr Purif 2002
16298142 Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization

Fonseca, IO, Magalhães, ML, Oliveira, JS, Silva, RG, Mendes, MA, Palma, MS, Santos, DS, Basso, LA

Protein Expr Purif 2006
Participants
Participates
Catalyst Activity

shikimate 3-dehydrogenase (NADP+) activity of AroE dimer [cytosol]

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