Shikimate results from hydration of DHS

Stable Identifier
R-MTU-964842
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Shikimate results from hydration of DHS
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The dimeric form of AroE catalyzes the hydration of dehydroshikimate. The reaction is reversible with high efficiency (Magalhaes et al, 2002; Fonseca et al, 2006).
Literature References
PubMed ID Title Journal Year
16298142 Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization

Fonseca, IO, Magalhães, ML, Oliveira, JS, Silva, RG, Mendes, MA, Palma, MS, Santos, DS, Basso, LA

Protein Expr Purif 2006
12356471 Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv

Magalhães, ML, Pereira, CP, Basso, LA, Santos, DS

Protein Expr Purif 2002
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Catalyst Activity

shikimate 3-dehydrogenase (NADP+) activity of AroE dimer [cytosol]

Physical Entity
AroE dimer [cytosol] (Mycobacterium tuberculosis)
Activity
shikimate 3-dehydrogenase (NADP+) activity (GO:0004764)
Authored
Stephan, R  (2010-09-13)
Reviewed
Warner, D  (2010-11-25)
Created
Jassal, B  (2010-09-20)
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