Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose

Stable Identifier
R-MTU-868657
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
ReviewStatus
5/5
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From the glucanotrehalose, the enzyme TreZ cleaves one molecule of trehalose, leaving a linear glucan that is two sugars shorter than before. This is the rate-limiting step in the TreYZ pathway of trehalose biosynthesis (De Smet et al, 2000).
Literature References
PubMed ID Title Journal Year
10658666 Three pathways for trehalose biosynthesis in mycobacteria

Young, DB, De Smet, KA, Robertson, BD, Brown, IN, Weston, A

Microbiology 2000
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Participates
Catalyst Activity

4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity of TreZ [cytosol]

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