Reactome | PolyUb-PKM-1 [cytosol]

PolyUb-PKM-1 [cytosol]

Stable Identifier

R-MMU-9861692

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

P52480

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P52480

Reference Genes

BioGPS Gene:18746

ENSEMBL:ENSMUSG00000032294

KEGG:mmu:18746

Monarch:18746

NCBI Gene:18746

UCSC:P52480

Reference Transcript

Other Identifiers

10585932

1417308_at

17518007

18746

4322533

4339663

4346264

4396503

4414496

4443145

4467229

4535384

4562763

4566187

4594835

4611577

4657209

4672199

4711272

4781553

4875896

5043586

5111159

5126343

5147652

5199730

5201207

5223822

5260620

5277756

5282807

5295398

5327561

5430689

5435279

5444097

5458900

5484370

5514753

5539530

5569202

96066_s_at

A_52_P150212

A_52_P328249

A_55_P2060107

A_55_P2738982

GE35898

GO:0000166

GO:0000287

GO:0003713

GO:0003729

GO:0003824

GO:0004713

GO:0004743

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005739

GO:0005783

GO:0005791

GO:0005829

GO:0005929

GO:0005975

GO:0006006

GO:0006091

GO:0006096

GO:0006325

GO:0006338

GO:0006355

GO:0006417

GO:0012501

GO:0016301

GO:0016740

GO:0030955

GO:0032869

GO:0035402

GO:0042803

GO:0043209

GO:0043226

GO:0045944

GO:0046872

GO:0055086

GO:0061621

GO:0140096

GO:1901135

GO:1903672

GO:2000767

ILMN_1236323

ILMN_2756041

Msa.2087.0_f_at

Msa.33222.0_f_at

mMC019524

x97047_f_at

Participates

as an output of

CTLH E3 ligase ubiquitinates PKM-1 (Mus musculus)

This entity regulates

Negatively

Pyruvate kinase dephosphorylates PEP to PYR (Mus musculus)

Other forms of this molecule

PKM [secretory granule lumen]

PKM [extracellular region]

PKM [ficolin-1-rich granule lumen]

PKM-1 [cytosol]

PKM [nucleoplasm]

Inferred From

PolyUb-PKM-1 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (polyubiquitin chain [cytosol]) at unknown position

Modification

polyubiquitin chain [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_001240812.1, NP_001365796.1, NP_035229.2, NP_001365797.1, XP_006510918.1, NP_001392420.1, NP_001365795.1, NP_001365799.1, NP_001365798.1

ENSEMBL

ENSMUSG00000032294, ENSMUSP00000034834, ENSMUST00000034834, ENSMUST00000163694, ENSMUSP00000128770

IntEnz

2.7.11.1

PRO

P52480

GlyGen

P52480

MGI

97591

HMDB Protein

HMDBP13273

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P20263 Pou5f1	2	Pou5f1 [nucleoplasm] (R-MMU-3245981) POU5F1 [nucleoplasm] (R-MMU-452472)	0.619	6
UniProt:P04156-PRO_0000025675 PRNP			0.599	5
UniProt:P26663 POLG			0.527	3