Mettl23 and Stgp4 (Gse) bind chromatin with H3.3 dimethylarginine-17

Stable Identifier
R-MMU-9822637
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Mettl23 and Stgp4 (Gse) bind chromatin with H3.3 dimethylarginine-17
Mettl23 binds both chromatin (probably via dimethylated arginine-17 of histone H3.3) and Stgp4 (Gse) (Hatanaka et al. 2017). Mettl23 and Stgp4 are required for localizing Tet3 to the pronuclei of the zygote (Hatanaka et al. 2017).
Literature References
PubMed ID Title Journal Year
28930672 Histone H3 Methylated at Arginine 17 Is Essential for Reprogramming the Paternal Genome in Zygotes

Hatanaka, Y, Tsusaka, T, Shimizu, N, Morita, K, Suzuki, T, Machida, S, Satoh, M, Honda, A, Hirose, M, Kamimura, S, Ogonuki, N, Nakamura, T, Inoue, K, Hosoi, Y, Dohmae, N, Nakano, T, Kurumizaka, H, Matsumoto, K, Shinkai, Y, Ogura, A

Cell Rep 2017
Participants
Input
Output
Orthologous Events
METTL23 and STGP4 (GSE) bind H3.3 dimethylarginine-17 (H3K17me2a) (Homo sapiens)
Authored
May, B  (2022-12-26)
Reviewed
Xie, W  (2023-08-08)
Created
May, B  (2022-12-27)
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