Expression of Tut4 in the embryo

Stable Identifier
R-MMU-9820790
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Tut4 in the embryo
During zygotic genome activation, expression of Tut4 is activated by Yap1:Tead4, possibly by Yap1:Tead4 directly binding the promoter of Tut4 (Sha et al. 2020). Yap1 is present in oocytes and maintained through zygotic genome activation. Tead4 is not present in oocytes and is activated during zygotic genome activation (Sha et al. 2020).
Literature References
PubMed ID Title Journal Year
31777931 Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse

Li, S, Fan, HY, Zhu, YZ, Shen, L, Ou, XH, Chen, L, Sha, QQ, Sun, XH, Jiang, Y

Nucleic Acids Res 2020
Participants
Input
Output
This event is regulated
Positively by
Regulator
Tead4:Yap1 [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of TUT4 in the embryo (Homo sapiens)
Authored
May, B  (2022-11-19)
Reviewed
Xie, W  (2023-08-08)
Created
May, B  (2022-11-20)
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