Expression of TUT4 in the embryo

Stable Identifier
R-HSA-9820806
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Expression of TUT4 in the embryo
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During zygotic genome activation, expression of Terminal uridylyltransferase 4 (TUT4) is activated by YAP1:TEAD4, possibly by YAP1:TEAD4 directly binding the promoter of TUT4 (inferred from mouse homologs). In mice, Yap1 is present in oocytes and maintained through zygotic genome activation. Tead4 is not present in oocytes and is activated during zygotic genome activation (Sha et al. 2020).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
TEAD4:YAP1 [nucleoplasm] (Homo sapiens)
Inferred From
Expression of Tut4 in the embryo (Mus musculus)
Authored
May, B  (2022-11-19)
Reviewed
Xie, W  (2023-08-08)
Created
May, B  (2022-11-20)
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