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Protonated weak acid translocates across the plasma membrane
Stable Identifier
R-MMU-9750040
Type
Reaction [transition]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SBML
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Level 2
Level 3
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Protonated weak acids such as acetic acid and citric acid are uncharged and are therefore able to diffuse across lipid membranes according to the concentration gradient. Passive diffusion of protonated weak acids into type III taste cells contributes to sour taste (Huang et al. 2008).
Literature References
PubMed ID
Title
Journal
Year
18420705
Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste
Huang, YA
,
Maruyama, Y
,
Stimac, R
,
Roper, SD
J Physiol
2008
Participants
Input
weak acid [extracellular region]
Output
weak acid [cytosol]
Orthologous Events
Protonated weak acid translocates across the plasma membrane (Homo sapiens)
Authored
May, B (2021-08-09)
Reviewed
Jiang, P (2021-08-11)
Created
May, B (2021-08-09)
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