Gata4, Gata6, and Isl1:Ldb1 bind the Hand2 gene

Stable Identifier
R-MMU-9735311
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
3/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Gata4, Gata6, and Isl1:Ldb1 bind the Hand2 gene
Gata4 and Gata6 (McFadden et al. 2000, He et al. 2011) and Isl1:Ldb1 (Caputo et al. 2015, Gao et al. 2019) bind the promoter of the Hand2 gene.
Literature References
PubMed ID Title Journal Year
21415370 Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

He, A, Ma, Q, Kong, SW, Pu, WT

Proc Natl Acad Sci U S A 2011
31024170 Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate

Cordero, J, Bhattacharya, S, Gao, R, Günther, S, Liang, X, Braun, T, Yuan, X, Cheedipudi, S, Dobreva, G, Zhang, Q, Ren, Y, Kuenne, C, Jiang, X, Chen, Y, Evans, SM, Sun, Y, Caputo, L, Barreto, G

Cell Res 2019
26321200 The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors

Looso, M, Kolovos, P, Soler, E, Laugwitz, KL, Witzel, HR, van IJcken, WF, Braun, T, Cheedipudi, S, Mylona, A, Dobreva, G, Grosveld, F, Evans, SM, Caputo, L

Cell Stem Cell 2015
11076755 A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart

Charité, J, McFadden, DG, Firulli, AB, Srivastava, D, Olson, EN, Richardson, JA

Development 2000
Participants
Input
Output
Orthologous Events
GATA4, GATA6, and ISL1:LDB1 bind the HAND2 gene (Homo sapiens)
Authored
May, B  (2021-06-23)
Created
May, B  (2021-06-24)
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