GATA4, GATA6, and ISL1:LDB1 bind the HAND2 gene

Stable Identifier
R-HSA-9735302
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
3/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
GATA4, GATA6 (Sharma et al. 2020), and ISL1:LDB1 bind the promoter of the HAND2 (dHAND) gene (inferred from mouse homologs).
Literature References
PubMed ID Title Journal Year
33054971 GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

Seidman, JG, Schmid, M, DeLaughter, DM, Chung, WK, Gelb, BD, Consortium, C, Conner, D, Goldmuntz, E, Jang, MY, Bernstein, D, Ward, T, Tristani-Firouzi, M, Toepfer, CN, Kim, Y, Porter, G, Willcox, JA, Tai, A, Agarwal, R, Srivastava, D, Sharma, A, Neyazi, M, Wasson, LK, Kim, S, DePalma, SR, Morton, SU, Seidman, CE, Pereira, AC, Gorham, JM

Elife 2020
Participants
Participates
Inferred From
Authored
Created
Cite Us!