Adcy3:Gnal:GTP converts ATP to cAMP

Stable Identifier
R-MMU-9713712
Type
Reaction [transition]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Adcy3:Gnal:GTP converts ATP to cAMP
The interaction of Gnal:GTP with Adcy3 activates Adcy3 to convert ATP to cyclic AMP (cAMP) (Washburn et al. 2002, Wang et al. 2006, Wang et al. 2011).
Literature References
PubMed ID Title Journal Year
12200344 Comparison of mechanical agitation and calcium shock methods for preparation of a membrane fraction enriched in olfactory cilia

Washburn, KB, Turner, TJ, Talamo, BR

Chem Senses 2002
21150908 Maternal behavior is impaired in female mice lacking type 3 adenylyl cyclase

Wang, Z, Storm, DR

Neuropsychopharmacology 2011
16837584 Pheromone detection in male mice depends on signaling through the type 3 adenylyl cyclase in the main olfactory epithelium

Wang, Z, Balet Sindreu, C, Li, V, Nudelman, A, Chan, GC, Storm, DR

J Neurosci 2006
Participants
Input
Output
Catalyst Activity

adenylate cyclase activity of Adcy3:Gnal:GTP [plasma membrane]

Physical Entity
Adcy3:Gnal:GTP [plasma membrane] (Mus musculus)
Activity
adenylate cyclase activity (GO:0004016)
Orthologous Events
ADCY3:GNAL:GTP converts ATP to cAMP (Homo sapiens)
Authored
May, B  (2021-01-26)
Reviewed
Raimondi, F  (2021-08-02)
Created
May, B  (2021-01-31)
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