ADCY3:GNAL:GTP converts ATP to cAMP

Stable Identifier
R-HSA-9712183
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
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ADCY3:GNAL:GTP converts ATP to cAMP
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The interaction of GNAL:GTP with ADCY3 activates ADCY3 to convert ATP to cyclic AMP (cAMP) (inferred from mouse homologs and rat homologs).

Literature References
PubMed ID Title Journal Year
15598656 Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants

Shirokova, E, Schmiedeberg, K, Bedner, P, Niessen, H, Willecke, K, Raguse, JD, Meyerhof, W, Krautwurst, D

J Biol Chem 2005
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Output
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as an event of
Catalyst Activity

adenylate cyclase activity of ADCY3:GNAL:GTP [plasma membrane]

Physical Entity
ADCY3:GNAL:GTP [plasma membrane] (Homo sapiens)
Activity
adenylate cyclase activity (GO:0004016)
Inferred From
Adcy3:Gnal:GTP converts ATP to cAMP (Rattus norvegicus)
Adcy3:Gnal:GTP converts ATP to cAMP (Mus musculus)
Authored
May, B  (2021-01-11)
Reviewed
Raimondi, F  (2021-08-02)
Created
May, B  (2021-01-16)
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