Reactome | Sla2 [cytosol]

Sla2 [cytosol]

Stable Identifier

R-MMU-9706161

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

SLA2, Q8R4L0

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8R4L0

Gene Names

Sla2

Reference Genes

BioGPS Gene:77799 Sla2

ENSEMBL:ENSMUSG00000027636

KEGG Gene (Mus musculus):77799 Sla2

Monarch:77799 Sla2

NCBI Gene:77799 Sla2

UCSC:Q8R4L0 Sla2

Reference Transcript

Other Identifiers

10489055

116262_at

139816_f_at

1437504_at

1451492_at

17393579

4624065

4885884

4928558

5087126

5108745

5186789

5223543

5226647

5386907

5461104

5570569

5610839

77799

A_52_P56682

GE1439024

GO:0000122

GO:0002250

GO:0002376

GO:0003674

GO:0005070

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005770

GO:0005794

GO:0005886

GO:0005942

GO:0006629

GO:0007165

GO:0008150

GO:0009058

GO:0009966

GO:0016020

GO:0030234

GO:0030674

GO:0031410

GO:0032991

GO:0034641

GO:0035591

GO:0042110

GO:0043226

GO:0043231

GO:0043551

GO:0046854

GO:0046935

GO:0047485

GO:0050849

GO:0050860

ILMN_1236595

ILMN_1237226

ILMN_2474239

mMC008132

Participant Of

input

Active FLT3 binds to SLA2

hasComponent

active FLT3:SLA2 [plasma membrane]

Inferred From

SLA2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006500468.1, NP_084259.1

Ensembl

ENSMUSG00000027636, ENSMUST00000029164, ENSMUSP00000029164, ENSMUSP00000105189, ENSMUST00000109561

PRO

Q8R4L0

MGI

1925049

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36888 FLT3	144	FLT3 N676D [plasma membrane] (R-HSA-9702895) FLT3 F691I [plasma membrane] (R-HSA-9702900) FLT3 R834Q [plasma membrane] (R-HSA-9691899) FLT3 Y572C [plasma membrane] (R-HSA-9691902) FLT3 A848P [plasma membrane] (R-HSA-9702909) FLT3 A627P [plasma membrane] (R-HSA-9699448) FLT3 F621L [plasma membrane] (R-HSA-9699426) p-Y768,Y969 FLT3 [plasma membrane] (R-HSA-9698405) Ub-pY FLT3 [endosome membrane] (R-HSA-9706174) Ub-pY FLT3 [plasma membrane] (R-HSA-9706171) FLT3 V592G [plasma membrane] (R-HSA-9691071) FLT3 Y589_F590insFYVDFREYEYDLKWEF [plasma membrane] (R-HSA-9697939) FLT3 F590G Y591D [plasma membrane] (R-HSA-9691062) FLT3 F594L [plasma membrane] (R-HSA-9691058) FLT3 E611_F612insGDNEYFYVDFREYEYDLKWEFPRENLE [plasma membrane] (R-HSA-9699433) FLT3 V579A [plasma membrane] (R-HSA-9691051) FLT3 Y599_D600insGLYVDFREYEY [plasma membrane] (R-HSA-9696044) FLT3 Y591_V592insVDFREDREHH [plasma membrane] (R-HSA-9696043) FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane] (R-HSA-9690076) FLT3 E598_Y599insGLVQVTGSSDNEYFYVDFREYE [plasma membrane] (R-HSA-9696033) FLT3 Y591_V592insVDFREYEYDH [plasma membrane] (R-HSA-9691903) FLT3 F612_G613insGYVDFREYEYDLKWEFRPRENLF [plasma membrane] (R-HSA-9696038) FLT3 Y599_F600insFYVDFREYEYDLKWEF [plasma membrane] (R-HSA-9690084) FLT3 E598_Y599insYDLKWEFRRENLEFG [plasma membrane] (R-HSA-9696037) FLT3 N609_L610insSSDNEYFYVDFREYEYDLKW [plasma membrane] (R-HSA-9690086) FLT3 F594_R595insREYEYDL [plasma membrane] (R-HSA-9696032) FLT3 L601_K602insREYEYDL [plasma membrane] (R-HSA-9696048) FLT3 N609_L610insSSDNEYFYVDFREYEYDLKWEFPREN [plasma membrane] (R-HSA-9690074) FLT3 E596_Y597insRTDFRE [plasma membrane] (R-HSA-9699428) FLT3 D586_E587insEYFYVDFREY [plasma membrane] (R-HSA-9690083) FLT3 E598_Y599insFYVDFREY [plasma membrane] (R-HSA-9699437) FLT3 V592A [plasma membrane] (R-HSA-9691070) FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane] (R-HSA-9696042) FLT3 E598_Y599insVDFREYE [plasma membrane] (R-HSA-9699445) FLT3 E598_Y599insFDFREYE [plasma membrane] (R-HSA-9696041) FLT3 K602_W603insYEYDLK [plasma membrane] (R-HSA-9683381) FLT3 L610_E611insLKWEFPRENL [plasma membrane] (R-HSA-9699438) FLT3 V579L [plasma membrane] (R-HSA-9691073) FLT3 F594V [plasma membrane] (R-HSA-9691061) FLT3 F594I [plasma membrane] (R-HSA-9691068) FLT3 V579E [plasma membrane] (R-HSA-9691057) FLT3 V592D [plasma membrane] (R-HSA-9691069) FLT3 V579I [plasma membrane] (R-HSA-9691056) FLT3 F594S [plasma membrane] (R-HSA-9691067) FLT3 D835del [plasma membrane] (R-HSA-9695715) FLT3 K663Q [plasma membrane] (R-HSA-9691908) FLT3 I836del [plasma membrane] (R-HSA-9695714) FLT3 D835N [plasma membrane] (R-HSA-9682321) FLT3 D835V [plasma membrane] (R-HSA-9682323) FLT3 Y842C [plasma membrane] (R-HSA-9699435) FLT3 D835H [plasma membrane] (R-HSA-9682304) FLT3 A627E_T628insYEYDLKWEFPRENLEFGKVLGSGAFGKVMNA [plasma membrane] (R-HSA-9691894) FLT3 I836LInsD [plasma membrane] (R-HSA-9682360) FLT3 D835E [plasma membrane] (R-HSA-9682297) FLT3 D835A [plasma membrane] (R-HSA-9682290) FLT3 D835Y [plasma membrane] (R-HSA-9682353) FLT3 N676K [plasma membrane] (R-HSA-9695721) FLT3 N841I [plasma membrane] (R-HSA-9691895) FLT3 F691L [plasma membrane] (R-HSA-9695722) FLT3 D839G [plasma membrane] (R-HSA-9695718) FLT3 K633N [plasma membrane] (R-HSA-9691906) FLT3 D839N [plasma membrane] (R-HSA-9695720) FLT3 N841Y [plasma membrane] (R-HSA-9691909) FLT3 D835G [plasma membrane] (R-HSA-9682301) FLT3 K633R [plasma membrane] (R-HSA-9691898) FLT3 N841T [plasma membrane] (R-HSA-9691896) FLT3 D835F [plasma membrane] (R-HSA-9682313) FLT3 N676T [plasma membrane] (R-HSA-9695719) FLT3 N676S [plasma membrane] (R-HSA-9695717) FLT3 N841K [plasma membrane] (R-HSA-9691907) FLT3 D839H [plasma membrane] (R-HSA-9695713) FLT3 F691V [plasma membrane] (R-HSA-9695716) FLT3 N841H [plasma membrane] (R-HSA-9691900) FLT3 D839E [plasma membrane] (R-HSA-9695712) FLT3 Y842H [plasma membrane] (R-HSA-9699443) FLT3 S451F [plasma membrane] (R-HSA-9691901) p-6Y FLT3 N676K [plasma membrane] (R-HSA-9695738) p-6Y FLT3 D839G [plasma membrane] (R-HSA-9695737) p-6Y FLT3 D835A [plasma membrane] (R-HSA-9682391) p-6Y FLT3 I836del [plasma membrane] (R-HSA-9695742) p-6Y FLT3 D835H [plasma membrane] (R-HSA-9682372) p-6Y FLT3 D835del [plasma membrane] (R-HSA-9695736) p-6Y FLT3 D835Y [plasma membrane] (R-HSA-9682387) p-6Y FLT3 D835V [plasma membrane] (R-HSA-9682373) p-6Y FLT3 D835N [plasma membrane] (R-HSA-9682378) p-6Y FLT3 N841I [plasma membrane] (R-HSA-9691926) p-6Y FLT3 K663Q [plasma membrane] (R-HSA-9691942) p-6Y FLT3 F691L [plasma membrane] (R-HSA-9695734) p-6Y FLT3 Y842C [plasma membrane] (R-HSA-9699420) p-6Y FLT3 D835E [plasma membrane] (R-HSA-9682395) p-6Y FLT3 D839H [plasma membrane] (R-HSA-9695739) p-6Y FLT3 N841T [plasma membrane] (R-HSA-9691939) p-6Y FLT3 D839N [plasma membrane] (R-HSA-9695744) p-6Y FLT3 N676T [plasma membrane] (R-HSA-9695743) p-6Y FLT3 K633N [plasma membrane] (R-HSA-9691928) p-6Y FLT3 Y842H [plasma membrane] (R-HSA-9699449) p-6Y FLT3 N841K [plasma membrane] (R-HSA-9691925) p-6Y FLT3 D835F [plasma membrane] (R-HSA-9682376) p-6Y FLT3 N841H [plasma membrane] (R-HSA-9691932) p-6Y FLT3 K633R [plasma membrane] (R-HSA-9691940) p-6Y FLT3 D835G [plasma membrane] (R-HSA-9682389) p-6Y FLT3 F691V [plasma membrane] (R-HSA-9695741) p-6Y FLT3 N676S [plasma membrane] (R-HSA-9695745) p-6Y FLT3 N841Y [plasma membrane] (R-HSA-9691927) p-6Y FLT3 D839E [plasma membrane] (R-HSA-9695740) p-6Y FLT3 S451F [plasma membrane] (R-HSA-9691933) p-6Y FLT3 F590G Y591D [plasma membrane] (R-HSA-9691065) p-6Y FLT3 E596_Y597insRTDFRE [plasma membrane] (R-HSA-9699436) p-6Y FLT3 F594L [plasma membrane] (R-HSA-9691052) p-6Y FLT3 V592A [plasma membrane] (R-HSA-9691053) p-6Y FLT3 V579A [plasma membrane] (R-HSA-9691066) p-6Y FLT3 E611_F612insGDNEYFYVDFREYEYDLKWEFPRENLE [plasma membrane] (R-HSA-9699446) p-6Y FLT3 V592G [plasma membrane] (R-HSA-9691060) p-6Y FLT3 F594S [plasma membrane] (R-HSA-9691072) p-6Y FLT3 V579L [plasma membrane] (R-HSA-9691064) p-6Y FLT3 F594I [plasma membrane] (R-HSA-9691059) p-6Y FLT3 V579I [plasma membrane] (R-HSA-9691055) p-6Y FLT3 V592D [plasma membrane] (R-HSA-9691050) p-6Y FLT3 F594V [plasma membrane] (R-HSA-9691049) p-6Y FLT3 V579E [plasma membrane] (R-HSA-9691054) p-6Y FLT3 E598_Y599insVDFREYE [plasma membrane] (R-HSA-9699429) p-6Y FLT3 F594_R595insREYEYDL [plasma membrane] (R-HSA-9696035) p-6Y FLT3 E598_Y599insFYVDFREY [plasma membrane] (R-HSA-9699451) p-6Y FLT3 L601_K602insREYEYDL [plasma membrane] (R-HSA-9696049) p-6Y FLT3 L610_E611insLKWEFPRENL [plasma membrane] (R-HSA-9699417) p-6Y FLT3 A627E_T628insYEYDLKWEFPRENLEFGKVLGSGAFGKVMNA [plasma membrane] (R-HSA-9691924) p-6Y FLT3 N609_L610insSSDNEYFYVDFREYEYDLKW [plasma membrane] (R-HSA-9691931) p-6Y FLT3 N609_L610insSSDNEYFYVDFREYEYDLKWEFPREN [plasma membrane] (R-HSA-9691941) p-6Y FLT3 K602_W603insYEYDLK [plasma membrane] (R-HSA-9691930) p-6Y FLT3 E598_Y599insGLVQVTGSSDNEYFYVDFREYE [plasma membrane] (R-HSA-9696046) p-6Y FLT3 Y589_F590insFYVDFREYEYDLKWEF [plasma membrane] (R-HSA-9697935) p-6Y FLT3 E598_Y599insFDFREYE [plasma membrane] (R-HSA-9696031) p-6Y FLT3 E598_Y599insYDLKWEFRRENLEFG [plasma membrane] (R-HSA-9696039) p-6Y FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane] (R-HSA-9691943) p-6Y FLT3 Y600_D601insGLYVDFREYEY [plasma membrane] (R-HSA-9696034) p-6Y FLT3 Y599_F600insFYVDFREYEYDLKWEF [plasma membrane] (R-HSA-9691944) p-6Y FLT3 L610_E611insCSSDNEYFYVDFREYEYDLKWEFPRENL [plasma membrane] (R-HSA-9696047) p-6Y FLT3 Y591_V592insVDFREDREHH [plasma membrane] (R-HSA-9696045) p-6Y FLT3 F612_G613insGYVDFREYEYDLKWEFRPRENLF [plasma membrane] (R-HSA-9696036) p-6Y FLT3 D586_E587insEYFYVDFREY [plasma membrane] (R-HSA-9691936) p-6Y FLT3 Y591_V592insVDFREYEYDH [plasma membrane] (R-HSA-9691937) p-6Y FLT3 I836LInsD [plasma membrane] (R-HSA-9682380) Autophosphorylated FLT3 [plasma membrane] (R-HSA-9604780) FLT3 [plasma membrane] (R-HSA-6786756)	0.524	14

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