Reactome | SLA2 [cytosol]

SLA2 [cytosol]

Stable Identifier

R-HSA-9706161

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Src-like-adapter 2, SLAP2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H6Q3 SLA2

Gene Names

SLA2, C20orf156, SLAP2

Chain

initiator methionine:, chain:2-261

Reference Genes

BioGPS Gene:84174 SLA2

COSMIC (genes):SLA2 SLA2

CTD Gene:84174 SLA2

dbSNP Gene:84174 SLA2

ENSEMBL:ENSG00000101082 SLA2

HGNC:17329 SLA2

Monarch:84174 SLA2

NCBI Gene:84174 SLA2

OMIM:606577 SLA2

UCSC:Q9H6Q3 SLA2

Reference Transcript

Other Identifiers

11730341_a_at

11730342_x_at

11741760_a_at

1555688_PM_s_at

1555688_s_at

16918941

232234_PM_at

232234_at

3904512

3904513

3904514

3904515

3904516

3904517

3904518

3904519

3904520

3904521

3904522

3904524

3904525

3904526

8066038

83001_at

84174

A_23_P143173

A_33_P3368159

GO:0000122

GO:0002376

GO:0005515

GO:0005654

GO:0005737

GO:0005768

GO:0005770

GO:0005794

GO:0005829

GO:0005886

GO:0005942

GO:0006355

GO:0006629

GO:0010008

GO:0019724

GO:0031410

GO:0035591

GO:0042110

GO:0043226

GO:0043231

GO:0046854

GO:0046935

GO:0050776

GO:0050849

GO:0050851

GO:0050860

GO:0060090

GO:0098772

HMNXSV003022530

Hs.184062.3.A1_3p_at

Hs2.334489.2.S1_3p_s_at

ILMN_1673357

ILMN_2409720

PH_hs_0016426

TC20000815.hg

Participates

as an input of

Active FLT3 binds to SLA2 (Homo sapiens)

as a component of

active FLT3:SLA2 [plasma membrane] (Homo sapiens)

Inferred To

SLA2 [cytosol] (Bos taurus)

SLA2 [cytosol] (Canis familiaris)

Sla2 [cytosol] (Mus musculus)

Cross References

ENSEMBL

ENSP00000262866, ENST00000360672, ENSP00000353890, ENST00000262866

OpenTargets

ENSG00000101082

HPA

ENSG00000101082-SLA2

PRO

Q9H6Q3

Pharos - Targets

Q9H6Q3

PDB

4M4Z

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54646 PRKAA2	4	PRKAA2 [cytosol] (R-HSA-200405) p-T172-PRKAA2 [cytosol] (R-HSA-200417) p-T172-PRKAA2 [nucleoplasm] (R-HSA-164171) PRKAA2 [nucleoplasm] (R-HSA-163682)	0.556	3
UniProt:P57075-2 UBASH3A			0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2

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