Foxo6 binds G6pc gene promoter

Stable Identifier
R-MMU-9623187
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
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Foxo6 binds G6pc gene promoter
In fasted mouse liver cells, endogenous Foxo6 binds the promoter of the G6pc gene, encoding Glucose-6-phosphatase. Binding of Foxo6 to the G6pc gene promoter is negatively regulated by insulin (Ayala et al. 2011).
Literature References
PubMed ID Title Journal Year
10480625 Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence

Ayala, JE, Streeper, RS, Desgrosellier, JS, Durham, SK, Suwanichkul, A, Svitek, CA, Goldman, JK, Barr, FG, Powell, DR, O'Brien, RM

Diabetes 1999
Participants
This event is regulated
Orthologous Events
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