Gad2 gene expression is stimulated by Mecp2

Stable Identifier
R-MMU-9022930
Type
Reaction [omitted]
Species
Mus musculus
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General
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Gad2 gene expression is stimulated by Mecp2

Mouse Mecp2 stimulates transcription of the mouse Gad2 (Gad65) gene, encoding glutamate decarboxylase 2 (Chao et al. 2010, He et al. 2014).

Literature References
PubMed ID Title Journal Year
21068835 Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Chao, HT, Chen, H, Samaco, RC, Xue, M, Chahrour, M, Yoo, J, Neul, JL, Gong, S, Lu, HC, Heintz, N, Ekker, M, Rubenstein, JL, Noebels, JL, Rosenmund, C, Zoghbi, HY

Nature 2010
25297674 Conditional deletion of Mecp2 in parvalbumin-expressing GABAergic cells results in the absence of critical period plasticity

He, LJ, Liu, N, Cheng, TL, Chen, XJ, Li, YD, Shu, YS, Qiu, ZL, Zhang, XH

Nat Commun 2014
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