GAD2 gene expression is stimulated by MECP2

Stable Identifier
R-HSA-9022942
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
ReviewStatus
5/5
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GAD2 gene expression is stimulated by MECP2
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Based on studies in mice, MECP2 stimulates transcription of the GAD2 (GAD65) gene, encoding glutamate decarboxylase 2, an enzyme involved in GABA synthesis (Chao et al. 2010, He et al. 2014).

Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
MECP2:GAD2 gene [nucleoplasm] (Homo sapiens)
Active Unit
MECP2 [nucleoplasm]
Inferred From
Gad2 gene expression is stimulated by Mecp2 (Mus musculus)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-09-26)
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