Reactome | Sgk1 [cytosol]

Sgk1 [cytosol]

Stable Identifier

R-MMU-9022782

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Serine/threonine-protein kinase Sgk1 ecNumber2.7.11.1/ecNumber, SGK1_MOUSE

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Expression and Degradation (Mus musculus)
        
        Regulation of TP53 Degradation (Mus musculus)
        
        TORC2 complex phosphorylates SGK1 (Mus musculus)
        
        Sgk1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9WVC6 Sgk1

Gene Names

Sgk1, Sgk

Chain

chain:1-431

Reference Genes

BioGPS Gene:20393 Sgk1

KEGG:mmu:20393 Sgk1

Monarch:20393 Sgk1

NCBI Gene:20393 Sgk1

UCSC:Q9WVC6 Sgk1

Reference Transcript

Other Identifiers

10362073

135261_at

1416041_at

17232055

20393

4305308

4332083

4342754

4396530

4419491

4428259

4445782

4543278

4545625

4588118

4604794

4621766

4653566

4771836

4785242

4804521

4827503

4840053

4952428

4954598

4977269

5010157

5030798

5031398

5054017

5140555

5178336

5189915

5236562

5242526

5243907

5292453

5378202

5426556

5431090

5433118

5440065

5463222

5499205

5503524

5561538

97890_at

A_30_P01022456

A_30_P01022517

A_30_P01024074

A_30_P01029368

A_51_P118237

A_52_P178486

A_52_P352246

A_55_P2039416

GE106583

GE36073

GO:0003824

GO:0004672

GO:0004674

GO:0004712

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005739

GO:0005783

GO:0005789

GO:0005829

GO:0005886

GO:0006468

GO:0006883

GO:0006915

GO:0006974

GO:0007010

GO:0007019

GO:0007616

GO:0008092

GO:0008289

GO:0008542

GO:0010765

GO:0012501

GO:0015459

GO:0016607

GO:0016740

GO:0030307

GO:0031115

GO:0032869

GO:0032880

GO:0035091

GO:0035556

GO:0043066

GO:0043226

GO:0043402

GO:0043423

GO:0048156

GO:0048471

GO:0048812

GO:0050775

GO:0050877

GO:0098772

GO:0106310

GO:0140096

GO:1904045

ILMN_1213954

ILMN_1217874

ILMN_2466142

Msa.25610.0_s_at

Msa.32326.0_s_at

aa217550_s_at

mMC003046

mMC020746

Participates

as a member of

SGK1/2/3 [cytosol] (Mus musculus)

as an output of

Sgk1 gene expression is inhibited by Mecp2 (Mus musculus)

as an input of

TORC2 complex phosphorylates SGK1 (Mus musculus)

Other forms of this molecule

phospho-p-S422-SGK1 [cytosol]

phospho-p-T256,S422-SGK1 [cytosol]

phospho-p-T256,S422-SGK1 [nucleoplasm]

Inferred From

SGK1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001155322.1, NP_035491.1, NP_001155321.1, NP_001155320.1, NP_001155317.2, NP_001155319.1

ENSEMBL

ENSMUST00000092673, ENSMUSP00000020145, ENSMUST00000020145, ENSMUSP00000114074, ENSMUSP00000090343, ENSMUST00000120509

IntEnz

2.7.11.1

PRO

Q9WVC6

MGI

1340062

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Z2S7-3 TSC22D3			0.524	2