Src phosphorylates Robo3.1 in response to Ntn1

Stable Identifier
R-MMU-9011252
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Src phosphorylates Robo3.1 in response to Ntn1

In mouse neurons, Ntn1 (netrin-1)-mediated activation of Dcc, induces Src-mediated phosphorylation of Robo3.1 on a conserved tyrosine Y1019 (Zelina et al. 2014).

Literature References
PubMed ID Title Journal Year
25433640 Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution

Zelina, P, Blockus, H, Zagar, Y, Péres, A, Friocourt, F, Wu, Z, Rama, N, Fouquet, C, Hohenester, E, Tessier-Lavigne, M, Schweitzer, J, Roest Crollius, H, Chédotal, A

Neuron 2014
Participants
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of MyrG-p-Y424-Src [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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