Runx2 binds Gli3r

Stable Identifier
R-MMU-9008236
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Runx2 binds Gli3r

Mouse Gli3r, a repressive form of Gli3 generated in the Hedgehog "off" state, binds to Runx2 and inhibits binding of Runx2 to DNA (Ohba et al. 2008).

Literature References
PubMed ID Title Journal Year
18477452 Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity

Ohba, S, Kawaguchi, H, Kugimiya, F, Ogasawara, T, Kawamura, N, Saito, T, Ikeda, T, Fujii, K, Miyajima, T, Kuramochi, A, Miyashita, T, Oda, H, Nakamura, K, Takato, T, Chung, UI

Dev. Cell 2008
Participants
Orthologous Events
Authored
Reviewed
Created