Expression of Dec2 (Bhlhe41, Bhlhb3)

Stable Identifier
R-MMU-879716
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Dec2 (Bhlhe41, Bhlhb3)
The Dec2 (Bhlhe41, Bhlhb3) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the Dec2 promoter and activate transcription of Dec2.
Literature References
PubMed ID Title Journal Year
15147242 Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system

Hamaguchi, H, Fujimoto, K, Kawamoto, T, Noshiro, M, Maemura, K, Takeda, N, Nagai, R, Furukawa, M, Honma, S, Honma, K, Kurihara, H, Kato, Y

Biochem J 2004
Participants
Input
Output
This event is regulated
Positively by
Regulator
p-S97-Bmal1:p-T451,T461-Clock:Bhlhe41 gene [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of DEC2 (BHLHE41, BHLHB3) (Homo sapiens)
Authored
May, B  (2010-06-18)
Reviewed
Albrecht, U  (2010-06-23)
Delaunay, F  (2010-06-23)
Hirota, T  (2010-06-23)
Kay, SA  (2010-06-23)
Albrecht, U  (2025-03-06)
Created
May, B  (2010-06-23)
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