Expression of Dec2 (Bhlhe41, Bhlhb3)

Stable Identifier
R-MMU-879716
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
General
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PNG
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Medium
High
 | PPTX  | SBGN
Expression of Dec2 (Bhlhe41, Bhlhb3)

The Dec2 (Bhlhe41, Bhlhb3) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the Dec2 promoter and activate transcription of Dec2.

Literature References
PubMed ID Title Journal Year
15147242 Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system

Kurihara, H, Kato, Y, Noshiro, M, Honma, K, Honma, S, Furukawa, M, Nagai, R, Kawamoto, T, Hamaguchi, H, Maemura, K, Takeda, N, Fujimoto, K

Biochem J 2004
Participants
Input
Output
This event is regulated
Positively by
Regulator
p-Bmal1:p-Clock,Npas2:Bhlhe41 gene [nucleoplasm] (Mus musculus)
Summation

Bmal1:Clock (Arntl:Clock) heterodimers bind E-boxes in the promoter of the Dec2 (Bhlhe41, Bhlhb3) gene and activate transcription of the Dec2 gene.

Orthologous Events
Expression of DEC2 (BHLHE41, BHLHB3) (Homo sapiens)
Authored
May, B  (2010-06-18)
Reviewed
Delaunay, F  (2010-06-23)
Kay, SA  (2010-06-23)
Hirota, T  (2010-06-23)
Albrecht, U  (2010-06-23)
Created
May, B  (2010-06-23)
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