Reactome | Ifna12 [extracellular region]

Ifna12 [extracellular region]

Stable Identifier

R-MMU-877349-11

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

IFNA2, Q80SS5

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Interferon Signaling (Mus musculus)
    - Interferon alpha/beta signaling (Mus musculus)
      - Activation of JAK kinases (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Formation of p-STAT1 homodimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - IFN alpha/beta binds to IFNAR2 (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Phosphorylation of INFAR1 by TYK2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Phosphorylation of STAT2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Recruitment of IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Recruitment of STAT2 to p-IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Regulation of IFNA/IFNB signaling (Mus musculus)
        
        Dephosphorylation of JAK1 by SHP1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        Dephosphorylation of STAT1 by SHP2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        Dephosphorylation of TYK2 by PTP1B (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
      - Release of p-STAT2:p-STAT1 dimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna12 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q80SS5

Gene Names

Ifna12

Reference Genes

BioGPS Gene:242519 Ifna12

CTD Gene:242519 Ifna12

ENSEMBL:ENSMUSG00000073811

KEGG:mmu:242519 Ifna12

Monarch:242519 Ifna12

NCBI Gene:242519 Ifna12

UCSC:Q80SS5 Ifna12

Reference Transcript

RefSeq:NM_177361.2 Ifna12

Other Identifiers

101791_f_at

10514289

10514300

17427077

242519

4334235

4371400

4389014

4395248

4645351

4934969

4983925

5160574

5204390

5260048

5397851

5426068

5511596

5585809

A_52_P211172

A_55_P2100954

A_66_P127574

GO:0002250

GO:0002286

GO:0002312

GO:0002323

GO:0002376

GO:0005125

GO:0005126

GO:0005132

GO:0005576

GO:0005615

GO:0006952

GO:0006959

GO:0007165

GO:0043330

GO:0048018

GO:0051607

GO:0060337

GO:0098542

GO:0098772

ILMN_1233627

ILMN_1236929

mMC001595

Participates

as a member of

Homologues of IFNA2 [extracellular region] (Mus musculus)

Other forms of this molecule

Ifna12 [extracellular region]

Inferred From

IFNA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_796335.1

ENSEMBL

ENSMUST00000102806, ENSMUSP00000099870, ENSMUSG00000073811

PRO

Q80SS5

GlyGen

Q80SS5

MGI

2676324

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