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APAF1:ATP:CYCS [cytosol]
Stable Identifier
R-MMU-6804555
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Formation of apoptosome (Mus musculus)
CYCS binds to APAF1 (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
CYCS:APAF1 binds procaspase-9 (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Procaspase 9 forms dimer (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Regulation of the apoptosome activity (Mus musculus)
APAF1:CYCS binds APIP (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:CYCS:ATP:APIP [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
CASP9 is phosphorylated at T412 (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
APAF1:ATP [cytosol]
(Mus musculus)
Cycs [cytosol]
(Mus musculus)
Participates
as a component of
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
as an input of
CYCS:APAF1 binds procaspase-9 (Mus musculus)
as an output of
CYCS binds to APAF1 (Mus musculus)
Inferred From
APAF1:ATP:CYCS [cytosol]
(Homo sapiens)
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