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Cycs [cytosol]
Stable Identifier
R-MMU-6804633
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Activation of caspases through apoptosome-mediated cleavage (Mus musculus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Cleavage of Procaspase-7 by the apoptosome (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Formation of apoptosome (Mus musculus)
CYCS binds to APAF1 (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
CYCS:APAF1 binds procaspase-9 (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Cleavage of Procaspase‑9 to caspase‑9 (Mus musculus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Procaspase 9 forms dimer (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Regulation of the apoptosome activity (Mus musculus)
APAF1:CYCS binds APIP (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
APAF1:CYCS:ATP:APIP [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
CASP9 is phosphorylated at T412 (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
XIAP binds CASP9 (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
XIAP:apoptosome [cytosol] (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Cycs [cytosol] (Mus musculus)
Release of apoptotic factors from the mitochondria (Mus musculus)
Release of Cytochrome c from mitochondria (Mus musculus)
Cycs [cytosol] (Mus musculus)
Regulated Necrosis (Mus musculus)
Pyroptosis (Mus musculus)
Release of Cytochrome c from mitochondria (Mus musculus)
Cycs [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P62897 Cycs
Gene Names
Cycs
Chain
initiator methionine:, chain:2-105
Reference Genes
BioGPS Gene:13063 Cycs
ENSEMBL:ENSMUSG00000058927.7 Cycs
ENSEMBL:ENSMUSG00000063694.6 Cycs
KEGG Gene (Mus musculus):13063 Cycs
Monarch:13063 Cycs
NCBI Gene:13063 Cycs
UCSC:P62897 Cycs
Reference Transcript
RefSeq:NM_007808.4 Cycs
Other Identifiers
10462136
10528170
10544687
13063
1422483_a_at
1422484_at
1445484_at
1456071_a_at
17358271
17445624
17466723
17548102
17548541
4347980
4514332
4519208
4566451
4574449
4785496
4825407
4856522
4881230
4916502
4955466
4965740
4968474
4980738
5137958
5147358
5157354
5212314
5371995
5439110
5501281
5551760
98132_at
A_51_P163587
A_51_P261671
A_52_P82247
A_55_P1968958
A_55_P2020153
GE1457346
GE42481
GO:0003824
GO:0005634
GO:0005739
GO:0005758
GO:0005829
GO:0006091
GO:0006122
GO:0006123
GO:0006915
GO:0009055
GO:0012501
GO:0016491
GO:0019899
GO:0020037
GO:0022900
GO:0023052
GO:0042743
GO:0043209
GO:0043226
GO:0043293
GO:0046872
GO:0070469
GO:0097193
ILMN_1250564
ILMN_3076459
ILMN_3155380
Msa.2245.0_s_at
X01756_f_at
mMC021706
Participates
as a component of
Apaf1:ATP:Cycs [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
as an input of
CYCS binds to APAF1 (Mus musculus)
as an output of
Release of Cytochrome c from mitochondria (Mus musculus)
Other forms of this molecule
AcK-CYCS [mitochondrial intermembrane space]
apo-CYCS [mitochondrial inner membrane]
Cytochrome c (reduced) [mitochondrial inner membrane]
Cytochrome c (oxidised) [mitochondrial inner membrane]
CYCS [mitochondrial intermembrane space]
Inferred From
CYCS [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_031834.1
Ensembl
ENSMUSG00000058927
,
ENSMUSP00000124523
,
ENSMUST00000073080
,
ENSMUSP00000072829
,
ENSMUST00000161401
,
ENSMUSG00000063694
PRO
P62897
MGI
88578
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