Reactome | NDUFS7 [mitochondrial matrix]

NDUFS7 [mitochondrial matrix]

Stable Identifier

R-MMU-6788521

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

mitochondrial matrix

Synonyms

Q9DC70

Locations in the PathwayBrowser

Expand all

Metabolism (Mus musculus)

- Aerobic respiration and respiratory electron transport (Mus musculus)
  - Respiratory electron transport (Mus musculus)
    - Complex I biogenesis (Mus musculus)
      - IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - Intermediate 1 binds HP subcomplex to form Intermediate 2 (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - NDUF subunits bind to form the IP subcomplex (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - NUBPL transfers 4Fe-4S to Complex I subunits (Mus musculus)
        
        NDUF subunits [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        NDUF:4Fe-4S subunits [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 [mitochondrial inner membrane] (Mus musculus)
        
        IP subcomplex [mitochondrial matrix] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
        
        Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Mus musculus)
      - Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)
        
        NDUFS7 [mitochondrial matrix] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9DC70

Reference Genes

BioGPS Gene:75406

ENSEMBL:ENSMUSG00000020153

KEGG:mmu:75406

Monarch:75406

NCBI Gene:75406

UCSC:Q9DC70

Reference Transcript

Other Identifiers

10364744

1424313_a_at

1451312_at

162529_at

17235268

4315368

4317355

4417203

4524411

4600035

4648653

4741501

4814570

5063906

5305169

5401690

5421360

5432055

5444851

5533166

5605922

75406

A_55_P1974273

GE42329

GO:0003954

GO:0004497

GO:0005739

GO:0005743

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0015990

GO:0016020

GO:0016491

GO:0032981

GO:0042776

GO:0045271

GO:0046872

GO:0048038

GO:0051536

GO:0051539

GO:0055086

GO:0065003

GO:1901135

ILMN_2688763

mMC018403

Participates

as a member of

NDUF subunits [mitochondrial matrix] (Mus musculus)

as a component of

NDUFS7:4Fe-4S [mitochondrial matrix] (Mus musculus)

Inferred From

NDUFS7 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

XP_030101204.1, NP_083548.1

ENSEMBL

ENSMUSG00000020153, ENSMUSP00000020361, ENSMUST00000020361, ENSMUSP00000101003, ENSMUST00000105364

PRO

Q9DC70

MGI

1922656

GlyGen

Q9DC70

PDB

6G2J, 6ZTQ, 8UCA, 8RGP, 8XNR, 8XNT, 8XNS, 8IB9, 8XNU, 8XNZ, 8C2S, 7AK5, 7AK6, 8IAP, 8IB4, 8XNO, 8IC3, 6G72, 8XO0, 8XNX, 8XNP, 8XNV, 8IC2, 8XNQ, 8XNY, 8XNW, 8XNN, 8PW6, 8CA5, 8OLT, 8CA3, 8XNM, 8PW5, 8IBE, 8XNL, 8PW7, 7PSA, 8IBD, 8RGT, 8RGQ, 8OM1, 8RGR, 7B93, 6ZR2, 8IAO, 8IBA, 8IB5

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