Reactome | phospho-Il10ra [plasma membrane]

phospho-Il10ra [plasma membrane]

Stable Identifier

R-MMU-6784810

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-Y446-IL10RA, Q61727

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-10 signaling (Mus musculus)
      - IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
      - STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
      - p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Mus musculus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)
        
        phospho-Il10ra [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q61727

Gene Names

Il10ra

Reference Genes

BioGPS Gene:16154 Il10ra

ENSEMBL:ENSMUSG00000032089

KEGG:mmu:16154 Il10ra

Monarch:16154 Il10ra

NCBI Gene:16154 Il10ra

UCSC:Q61727 Il10ra

Reference Transcript

RefSeq:NM_008348.3 Il10ra

Other Identifiers

10593050

1448731_at

16154

17526492

4361859

4376577

4466009

4532876

4678844

4738066

4838961

4959064

5123655

5464095

5475774

96525_at

A_51_P235984

A_55_P2736330

GE34628

GO:0004920

GO:0005515

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0005929

GO:0010507

GO:0016020

GO:0016324

GO:0019221

GO:0022600

GO:0043226

GO:0046427

GO:0050728

GO:0060729

GO:0070086

GO:0140105

ILMN_1219946

L12120_s_at

mMC016450

Participates

as a component of

p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Mus musculus)

Other forms of this molecule

Il10ra [plasma membrane]

phospho-Il10ra [plasma membrane]

Inferred From

p-Y-IL10RA [plasma membrane] (Homo sapiens)

p-Y446-IL10RA [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 446 (in Homo sapiens)

Coordinate

446

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_032374.1

ENSEMBL

ENSMUSP00000034594, ENSMUST00000034594, ENSMUSG00000032089

PRO

Q61727

GlyGen

Q61727

MGI

96538