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TRAF3:NIK [cytosol]
Stable Identifier
R-MMU-5668511
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
TNFR2 non-canonical NF-kB pathway (Mus musculus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Mus musculus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Mus musculus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Mus musculus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Mus musculus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1/2 complex binds FN14:TWEAK (Mus musculus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAF3 binds BAFFR:BAFF (Mus musculus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAFs bind RANK:RANKL (Mus musculus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Mus musculus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Mus musculus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Mus musculus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Mus musculus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF3:NIK [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MAP3K14 [cytosol]
(Mus musculus)
Traf3 [cytosol]
(Mus musculus)
Participates
as an input of
TRAF3:NIK binds TRAF2:cIAP1/2 (Mus musculus)
as a component of
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
Inferred From
TRAF3:NIK [cytosol]
(Homo sapiens)
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