Mtf1 dimer:12Zn2+ binds Csrp1 gene

Stable Identifier
R-MMU-5660470
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
General
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PNG
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 | PPTX  | SBGN
Mtf1 dimer:12Zn2+ binds Csrp1 gene

The promoter of the Csrp1 gene contains 3 consensus metal response elements, at least one of which binds Mtf1 (Wimmer et al. 2005). Expression of Csrp1 is activated by cadmium via Mtf1.

Literature References
PubMed ID Title Journal Year
16221973 Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione

Georgiev, O, Wang, Y, Schaffner, W, Wimmer, U

Nucleic Acids Res. 2005
Participants
Input
Output
Orthologous Events
MTF1 dimer:12Zn2+ binds CSRP1 gene (Homo sapiens)
Authored
May, B  (2014-12-28)
Reviewed
Ford, D  (2017-01-27)
Created
May, B  (2015-01-05)
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