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CYP2D6 [endoplasmic reticulum membrane]
Stable Identifier
R-MMU-52679
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
endoplasmic reticulum membrane
Synonyms
Q9JKY7
Locations in the PathwayBrowser
Expand all
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Fatty acids (Mus musculus)
CYP2J2 oxidises ARA (Mus musculus)
Cytochrome P450 (CYP2J2 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Miscellaneous substrates (Mus musculus)
CYP2W1 oxidises INDOL (Mus musculus)
Cytochrome P450 (CYP2W1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Xenobiotics (Mus musculus)
CYP2C19 5-hydroxylates omeprazole (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Mus musculus)
Cytochrome P450 (CYP2C9 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 4-hydroxylates debrisoquine (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 reactions (Mus musculus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Benzene is hydroxylated to phenol (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Dehalogenation of carbon tetrachloride to form a free radical (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
MEOS oxidizes ethanol to acetaldehyde (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
O-atom dealkylation of dextromethorphan (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
Metabolism of lipids (Mus musculus)
Biosynthesis of specialized proresolving mediators (SPMs) (Mus musculus)
Biosynthesis of DHA-derived SPMs (Mus musculus)
Biosynthesis of maresins (Mus musculus)
Biosynthesis of maresin-like SPMs (Mus musculus)
CYPs hydroxylate DHA to 14(R)-HDHA (Mus musculus)
CYP1A2,2C8,2C9,2D6,2E1,3A4 [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 [endoplasmic reticulum membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9JKY7
Reference Genes
BioGPS Gene:56448
CTD Gene:56448
ENSEMBL:ENSMUSG00000061740
ENSEMBL:ENSMUSG00000061740.9
KEGG Gene (Mus musculus):56448
Monarch:56448
NCBI Gene:56448
UCSC:Q9JKY7
Reference Transcript
RefSeq:NM_001163472.1
RefSeq:NM_019823.4
Other Identifiers
10430851
111163_at
1419039_at
1419040_at
17319625
4393680
4418572
4477988
4539302
4556771
4601610
4755110
4764487
4799797
4923856
5018491
5040516
5067049
5144951
5402889
5569430
5585355
5602264
56448
A_51_P124126
A_51_P124132
A_51_P124133
A_52_P49391
GE37490
GO:0003824
GO:0004497
GO:0005506
GO:0005737
GO:0005739
GO:0005783
GO:0005789
GO:0006520
GO:0006587
GO:0006629
GO:0006805
GO:0007565
GO:0008207
GO:0008391
GO:0010033
GO:0016020
GO:0016491
GO:0016705
GO:0016712
GO:0019369
GO:0020037
GO:0022414
GO:0042416
GO:0042417
GO:0043226
GO:0043231
GO:0046872
GO:0062187
GO:0062188
GO:0062189
ILMN_1214498
mMC026263
Participates
as a member of
CYP1A2,2C8,2C9,2D6,2E1,3A4 [endoplasmic reticulum membrane] (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
as a candidate of
Cytochrome P450 (CYP2C9 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2J2 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2W1 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
Inferred From
CYP2D6 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001156944.1
,
NP_062797.3
Ensembl
ENSMUSG00000061740
,
ENSMUSP00000023083
,
ENSMUST00000023083
MGI
1929474
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